Diffuse Low-Grade Gliomas in Adults: Natural History, Interaction with the Brain, and New Individualized Therapeutic Strategies ebook

Pages 1-5. Duffau, Hugues, MD, PhD.

Pages 1-5.

The biology, behavior and management of diffuse low-grade gliomas (DLGG) in adults have been matters of controversy for many decades. However, recent technical and conceptual advances in genetics, imaging and treatments have paved the way towards individualized management.

from book Diffuse low-grade gliomas in adults: Natural history, interaction with the brain, and new individualized therapeutic strategies (p. 1-72). Diffuse Low-Grade Gliomas in Adults. Chapter · February 2013 with 4 Reads.

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Hugues Duffau, after his residency and habilitation 2002 at the University Paris VI, became Professor 2006 and Head of the Department of Neurosurgery, Montpellier, France in 2007. He is one of the leading experts in low grade glioma surgery and well known for his holistic view of the brain and his pursuit for changing paradigms in neurooncological surgery. For him, a deep understanding of anatomy, functional imaging, intraoperative mapping and neuropsycological assessments is mandatory to open new doors to personalized therapeutic strategies for patients.

Diffuse low-grade glioma grows, migrates along white matter tracts, and progresses to high-grade glioma

Diffuse low-grade glioma grows, migrates along white matter tracts, and progresses to high-grade glioma. Rather than a "wait and see" policy, an aggressive attitude is now recommended, with early surgery as the first therapy. Intraoperative mapping, with maximal resection according to functional boundaries, is associated with a longer overall survival (OS) while minimizing morbidity. New individualized management strategies should deal with the interactions between the course of this chronic disease, reaction brain remapping, and oncofunctional modulation elicited by serial treatments. This philosophy supports a personalized, functional, and preventive neuro-oncology.

Diffuse low-grade gliomas in adults : natural history, interaction with the brain, and new individualized . Guillaume Herbet, Gilles Lafargue, François Bonnetblanc, Sylvie Duffau Hugues Moritz-Gasser, Hugues Duffau.

Diffuse low-grade gliomas in adults : natural history, interaction with the brain, and new individualized therapeutic strategies. Is the right frontal cortex really crucial in the mentalizing network? A longitudinal study in patients with a slow-growing lesion. Quality of life in low - grade gliomas.

Автор: Duffau Название: Diffuse Low-Grade Gliomas in Adults Издательство: Springer .